Jumihaidokuto (Shi-Wei-Ba-Du-Tang), a Kampo Formula, Decreases the Disease Activity of Palmoplantar Pustulosis

• Published in: Dermatology Research and Practice Vol. 2016; no. 2016; pp. 39 - 42
• Main Authors: Shimizu, Tadamichi, Ueda, Chieko, Makino, Teruhiko, Furuichi, Megumi
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Limiteds 01-01-2016; Hindawi Publishing Corporation; Hindawi Limited
• Subjects: Acne; Clinical Study; Colleges & universities; Disease; Herbal medicine; Medicine; Patients; Psoriasis; Skin diseases; Japan
• ISSN: 1687-6105; 1687-6113
• DOI: 10.1155/2016/4060673

Palmoplantar pustulosis (PPP) is a chronic skin disease characterized by sterile intraepidermal pustules associated with erythematous scaling on the palms and soles. Jumihaidokuto is a traditional herbal medicine composed of ten medical plants and has been given to patients with suppurative skin disease in Japan. This study investigated the effect of jumihaidokuto on the disease activity in PPP patients (n=10). PPP patients were given jumihaidokuto (EKT-6; 6.0 g per day) for 4 to 8 weeks in addition to their prescribed medications. The results showed that the palmoplantar pustular psoriasis area and severity index (PPPASI) was decreased after the administration of jumihaidokuto (p<0.05). Therefore, Jumihaidokuto is seemingly effective against PPP.