Identification and Characterization of Inhibitors of Bacterial Enoyl-Acyl Carrier Protein Reductase

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Published in:	Antimicrobial Agents and Chemotherapy Vol. 48; no. 5; pp. 1541 - 1547
Main Authors:	LING, Losee L, JUN XIAN, YIBIN XIANG, MOIR, Donald T, ALI, Syed, BOLIN GENG, JUN FAN, MILLS, Debra M, ARVANITES, Anthony C, ORGUEIRA, Hernan, ASHWELL, Mark A, CARMEL, Gilles
Format:	Journal Article
Language:	English
Published:	Washington, DC American Society for Microbiology 01-05-2004
Subjects:	Antibiotics. Antiinfectious agents. Antiparasitic agents Bacillus subtilis Bacillus subtilis - drug effects Bacteria - drug effects Biological and medical sciences Cloning, Molecular Drug Evaluation, Preclinical Enoyl-(Acyl-Carrier-Protein) Reductase (NADH) Enzyme Inhibitors Enzyme Inhibitors - chemical synthesis Enzyme Inhibitors - pharmacology Escherichia coli Escherichia coli - drug effects Escherichia coli - enzymology Fatty Acids - biosynthesis Gene Expression Regulation, Bacterial - drug effects Kinetics Lac Operon - genetics Mechanisms of Action: Physiological Effects Medical sciences Microbial Sensitivity Tests Oxidoreductases Oxidoreductases - antagonists & inhibitors Oxidoreductases - biosynthesis Oxidoreductases - genetics Pharmacology. Drug treatments Pyridines Pyridines - chemical synthesis Pyridines - pharmacology Reverse Transcriptase Polymerase Chain Reaction Staphylococcus - drug effects Staphylococcus - genetics Staphylococcus - metabolism Staphylococcus aureus Structure-Activity Relationship Infection Characterization Enzyme Bacteriosis Identification Inhibitor Oxidoreductases Carrier protein Reductase
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Summary:	Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology. For an alternate route to AAC .asm.org, visit: AAC
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Corresponding author. Mailing address: Microbiotix, Inc., One Innovation Dr., Worcester, MA 01605. Phone: (339) 222-1756. Fax: (508) 757-1999. E-mail: dmoir@microbiotix.com.
ISSN:	0066-4804 1098-6596
DOI:	10.1128/aac.48.5.1541-1547.2004