Clinical Aspects and Management of Levodopa-Induced Dyskinesia

In Parkinson's disease, one of the most troublesome dilemmas is the treatment of levodopa-induced dyskinesia. After a few years, chronic treatment with levodopa is associated with the development of dyskinesias. Strategies to delay or to reduce dyskinesias are based on the change of levodopa do...

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Bibliographic Details
Published in:Parkinson's disease Vol. 2012; no. 2012; pp. 560 - 571
Main Authors: Calabresi, Paolo, Cardaioli, Gabriela, Murasecco, Donatella, Sacchini, Elisa, Marsili, Erica, Simoni, Simone, Tambasco, Nicola, Rossi, Aroldo
Format: Journal Article
Language:English
Published: Cairo, Egypt Hindawi Limiteds 01-01-2012
Hindawi Publishing Corporation
Hindawi Limited
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Summary:In Parkinson's disease, one of the most troublesome dilemmas is the treatment of levodopa-induced dyskinesia. After a few years, chronic treatment with levodopa is associated with the development of dyskinesias. Strategies to delay or to reduce dyskinesias are based on the change of levodopa dosing or the early use of dopamine agonists. Dopamine agonists with different pharmacological profile are available. Our paper was aimed to analyse the clinical impact and the management of dyskinesias with dopamine agonists.
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Academic Editor: Gilberto Fisone
ISSN:2042-0080
2090-8083
2042-0080
DOI:10.1155/2012/745947