In Vitro Inhibition of Hepadnavirus Polymerases by the Triphosphates of BMS-200475 and Lobucavir

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Published in:	Antimicrobial Agents and Chemotherapy Vol. 42; no. 12; pp. 3200 - 3208
Main Authors:	SEIFER, M, HAMATAKE, R. K, COLONNO, R. J, STANDRING, D. N
Format:	Journal Article
Language:	English
Published:	Washington, DC American Society for Microbiology 01-12-1998
Subjects:	Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Antiviral Agents - pharmacology Biological and medical sciences Deoxyguanosine Deoxyguanosine - analogs & derivatives Deoxyguanosine - pharmacology DNA-Directed RNA Polymerases DNA-Directed RNA Polymerases - antagonists & inhibitors Duck hepatitis B virus Enzyme Inhibitors Enzyme Inhibitors - pharmacology Guanine Guanine - analogs & derivatives Guanine - pharmacology Hepadnaviridae Hepadnaviridae - enzymology Hepadnavirus Hepatitis B virus Hepatitis B virus - drug effects Hepatitis B virus - enzymology Hepatitis B Virus, Duck - drug effects Hepatitis B Virus, Duck - enzymology Hepatitis B Virus, Woodchuck - drug effects Hepatitis B Virus, Woodchuck - enzymology Humans Kinetics Medical sciences Nucleic Acid Synthesis Inhibitors Pharmacology. Drug treatments Phosphates RNA-Directed DNA Polymerase - metabolism Structure-Activity Relationship Woodchuck hepatitis virus Human Duck hepatitis B virus Purine nucleoside Guanosine Triphosphates In vitro Virus Avihepadnavirus Hepadnaviridae Lobucavir Analog Antiviral Replication Mechanism of action
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Summary:	Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology. For an alternate route to AAC .asm.org, visit: AAC
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 Present address: Schering-Plough Research Institute, Kenilworth, NJ 07033-0539. Present address: GlaxoWellcome, Research Triangle Park, NC 27709. Corresponding author. Present mailing address: Schering-Plough Research Institute, 2015 Galloping Hill Rd., Kenilworth, NJ 07033-0539. Phone: (908) 740-7446. Fax: (908) 740-3918. E-mail: david.standring@spcorp.com.
ISSN:	0066-4804 1098-6596
DOI:	10.1128/aac.42.12.3200