Facultative Sterol Uptake in an Ergosterol-Deficient Clinical Isolate of Candida glabrata Harboring a Missense Mutation in ERG11 and Exhibiting Cross-Resistance to Azoles and Amphotericin B

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Published in:	Antimicrobial Agents and Chemotherapy Vol. 56; no. 8; pp. 4223 - 4232
Main Authors:	HULL, Claire M, PARKER, Josie E, BADER, Oliver, WEIG, Michael, GROSS, Uwe, WARRILOW, Andrew G. S, KELLY, Diane E, KELLY, Steven L
Format:	Journal Article
Language:	English
Published:	Washington, DC American Society for Microbiology 01-08-2012
Subjects:	Amphotericin B Amphotericin B - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal Agents Antifungal Agents - pharmacology Azoles Azoles - pharmacology Base Sequence Biological and medical sciences Biological Transport Candida glabrata Candida glabrata - drug effects Candida glabrata - genetics Candida glabrata - isolation & purification Candida glabrata - metabolism Drug Resistance, Multiple, Fungal Drug Resistance, Multiple, Fungal - genetics Ergosterol - metabolism Fluconazole - pharmacology Fungal Proteins - genetics Humans Mechanisms of Resistance Medical sciences Microbial Sensitivity Tests Mutation, Missense Pharmacology. Drug treatments Pyrimidines - pharmacology Saccharomyces cerevisiae - metabolism Sequence Analysis, DNA Sterol 14-Demethylase Sterol 14-Demethylase - genetics Sterols - metabolism Triazoles - pharmacology Voriconazole Human Ergosterol Yeast Azole derivatives Lipids Candida glabrata Uptake Fungi Antiprotozoal agent Antibiotic Antifungal agent Missense mutation Amphotericin B Polyenic compound Parasiticide Cross resistance Fungi Imperfecti Clinical isolate Sterol
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Summary:	Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology. For an alternate route to AAC .asm.org, visit: AAC
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0066-4804 1098-6596
DOI:	10.1128/AAC.06253-11