Ventilation/Perfusion SPECT for Diagnosis of Pulmonary Embolism and Other Diseases

• Published in: International Journal of Molecular Imaging Vol. 2011; no. 2011; pp. 271 - 277
• Main Authors: Bajc, Marika, Jonson, Björn
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Limiteds 2011; Hindawi Puplishing Corporation; Hindawi Publishing Corporation; Hindawi Limited
• Subjects: Advantages; Aerosols; Anatomy & physiology; Atoms & subatomic particles; Cardiac and Cardiovascular Systems; Clinical Medicine; Gases; Kardiologi; Klinisk medicin; Lungmedicin och allergi; Medical and Health Sciences; Medical imaging; Medicin och hälsovetenskap; Pneumonia; Respiratory Medicine and Allergy; Review; Studies; Tomography; Ventilation
• ISSN: 2090-1712; 2090-1720
• DOI: 10.1155/2011/682949

V/PSPECT has the potential to become a first hand tool for diagnosis of pulmonary embolism based on standardized technology and new holistic interpretation criteria. Pretest probability helps clinicians choose the most appropriate objective test for diagnosis or exclusion of PE. Interpretation should also take into account all ventilation and perfusion patterns allowing diagnosis of other cardiopulmonary diseases than PE. In such contexts, V/PSPECT has excellent sensitivity and specificity. Nondiagnostic reports are ≤3%. V/PSPECT has no contraindication; it is noninvasive and has very low radiation exposure. Moreover, acquisition time for V/PSPECT is only 20 minutes. It allows quantification of PE extension which has an impact on individual treatment. It is uniquely useful for followup and research.