Pharmacokinetics of Sulfobutylether-Beta-Cyclodextrin and Voriconazole in Patients with End-Stage Renal Failure during Treatment with Two Hemodialysis Systems and Hemodiafiltration

• Published in: Antimicrobial Agents and Chemotherapy Vol. 54; no. 6; pp. 2596 - 2602
• Main Authors: HAFNER, Verena, CZOCK, David, BURHENNE, Jürgen, RIEDET, Klaus-Dieter, BOMMER, Jürgen, MIKUS, Gerd, MACHLEIDT, Christoph, WEINREICH, Thomas, HAEFELI, Walter E
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01-06-2010; American Society for Microbiology (ASM)
• Subjects: Adult; Aged; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antifungal Agents; Antifungal Agents - administration & dosage; Antifungal Agents - pharmacokinetics; beta-Cyclodextrins; beta-Cyclodextrins - administration & dosage; beta-Cyclodextrins - pharmacokinetics; Biological and medical sciences; Cross-Over Studies; Emergency and intensive care: renal failure. Dialysis management; Female; Half-Life; Hemodiafiltration; Humans; Infusions, Intravenous; Intensive care medicine; Kidney Failure, Chronic; Kidney Failure, Chronic - metabolism; Kidney Failure, Chronic - therapy; Male; Medical sciences; Metabolic Clearance Rate; Middle Aged; Nephrology. Urinary tract diseases; Nephropathies. Renovascular diseases. Renal failure; Pharmacology; Pharmacology. Drug treatments; Pyrimidines; Pyrimidines - administration & dosage; Pyrimidines - pharmacokinetics; Renal Dialysis; Renal Dialysis - methods; Renal failure; Solvents; Triazoles; Triazoles - administration & dosage; Triazoles - pharmacokinetics; Voriconazole; Kidney disease; Human; Urinary system disease; Chronic renal failure; Hemodialysis; Azole derivatives; Oligosaccharide; Patient; β-Cyclodextrin; Cyclodextrin; Antifungal agent; Treatment; Voriconazole; Triazole derivatives; Inclusion compound; Pharmacokinetics
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.01540-09

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