Population Analysis of Weight-, Age-, and Sex-Related Differences in the Pharmacokinetics of Lopinavir in Children from Birth to 18 Years

• Published in: Antimicrobial Agents and Chemotherapy Vol. 50; no. 11; pp. 3548 - 3555
• Main Authors: JULLIEN, Vincent, URIEN, Saïk, FIRTION, Ghislaine, PONS, Gérard, BLANCHE, Stéphane, TRELUYER, Jean-Marc, HIRT, Déborah, DELAUGERRE, Constance, REY, Elisabeth, TEGLAS, Jean-Paul, VAZ, Paula, ROUZIOUX, Christine, CHAIX, Marie-Laure, MACASSA, Eugenia
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01-11-2006
• Subjects: Adolescent; Age Factors; Algorithms; Anti-HIV Agents; Anti-HIV Agents - pharmacokinetics; Antibiotics. Antiinfectious agents. Antiparasitic agents; Area Under Curve; Biological and medical sciences; Body Weight; Child; Child, Preschool; Chromatography, High Pressure Liquid; Female; Humans; Infant; Infant, Newborn; Lopinavir; Male; Medical sciences; Models, Statistical; Pharmacology; Pharmacology. Drug treatments; Population; Pyrimidinones; Pyrimidinones - pharmacokinetics; Reproducibility of Results; Retrospective Studies; Sex Factors; Spectrophotometry, Ultraviolet; Human; Antiretroviral agent; Enzyme; Lopinavir; Sex; Enzyme inhibitor; Birth; Weight; Peptidases; Hydrolases; Antiviral; Pharmacokinetics; Child; Protease inhibitor; Age
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.00943-05

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