Nickel-Catalyzed Enantioselective Reductive Cross-Coupling Reactions

Nickel-Catalyzed Enantioselective Reductive Cross-Coupling Reactions

Nickel-catalyzed reductive cross-coupling reactions have emerged as powerful methods to join two electrophiles. These reactions have proven particularly useful for the coupling of sec-alkyl electrophiles to form stereogenic centers; however, the development of enantioselective variants remains chall...

Full description

Saved in:
Bibliographic Details
Published in:ACS catalysis Vol. 10; no. 15; pp. 8237 - 8246
Main Authors: Poremba, Kelsey E, Dibrell, Sara E, Reisman, Sarah E
Format: Journal Article
Language:English
Published: United States American Chemical Society 07-08-2020
Subjects:
cross-electrophile coupling
asymmetric catalysis
reductive cross-coupling
nickel catalysis
enantioselective
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Nickel-catalyzed reductive cross-coupling reactions have emerged as powerful methods to join two electrophiles. These reactions have proven particularly useful for the coupling of sec-alkyl electrophiles to form stereogenic centers; however, the development of enantioselective variants remains challenging. In this Perspective, we summarize the progress that has been made toward Ni-catalyzed enantioselective reductive cross-coupling reactions.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:2155-5435
2155-5435
DOI:10.1021/acscatal.0c01842