Oseltamivir-Ribavirin Combination Therapy for Highly Pathogenic H5N1 Influenza Virus Infection in Mice

• Published in: Antimicrobial Agents and Chemotherapy Vol. 52; no. 11; pp. 3889 - 3897
• Main Authors: Ilyushina, Natalia A, Hay, Alan, Yilmaz, Neziha, Boon, Adrianus C M, Webster, Robert G, Govorkova, Elena A
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01-11-2008; American Society for Microbiology (ASM)
• Subjects: Animals; Antiviral Agents; Antiviral Agents - administration & dosage; Chemokines - biosynthesis; Cytokines - biosynthesis; Drug Interactions; Drug Therapy, Combination; Female; Influenza A Virus, H5N1 Subtype; Influenza A Virus, H5N1 Subtype - drug effects; Influenza A Virus, H5N1 Subtype - pathogenicity; Influenza A Virus, H5N1 Subtype - physiology; Influenza virus; Lung - drug effects; Lung - physiopathology; Lung - virology; Mice; Mice, Inbred BALB C; Neuraminidase - antagonists & inhibitors; Orthomyxoviridae Infections; Orthomyxoviridae Infections - drug therapy; Orthomyxoviridae Infections - physiopathology; Orthomyxoviridae Infections - virology; Oseltamivir; Oseltamivir - administration & dosage; Ribavirin; Ribavirin - administration & dosage; Virus Replication - drug effects
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.01579-07

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