Inhibition of theophylline clearance by coadministered ofloxacin without alteration of theophylline effects

• Published in: Antimicrobial Agents and Chemotherapy Vol. 31; no. 3; pp. 375 - 378
• Main Authors: GREGOIRE, S. L, GRASELA, T. H. JR, FREER, J. P, TACK, K. J, SCHENTAG, J. J
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01-03-1987
• Subjects: Adolescent; Adult; Anti-Infective Agents; Anti-Infective Agents - pharmacology; Antibacterial agents; Antibiotics. Antiinfectious agents. Antiparasitic agents; Biological and medical sciences; Drug Interactions; Humans; Kinetics; Male; Medical sciences; Metabolic Clearance Rate - drug effects; Ofloxacin; Oxazines; Oxazines - pharmacology; Pharmacology. Drug treatments; Research Article; Structure-Activity Relationship; Theophylline; Theophylline - metabolism; Theophylline - pharmacology; Human; Drug combination; Bronchodilator; Oral administration; Theophyllin; Drug interaction; Xanthine derivatives; Clearance; Antibacterial agent; Normal; Pharmacokinetics
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.31.3.375

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