Mechanism of Activation and Inactivation of Gq/Phospholipase C-β Signaling Nodes

Harden et al examine C-beta signaling nodes with regard to the mechanism of activation and inactivation of Gq/phospholipase.

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Bibliographic Details
Published in:	Chemical reviews Vol. 111; no. 10; pp. 6120 - 6129
Main Authors:	Harden, T. Kendall, Waldo, Gary L, Hicks, Stephanie N, Sondek, John
Format:	Journal Article
Language:	English
Published:	United States American Chemical Society 12-10-2011
Subjects:	Activation Animals Biocatalysis Enzymes GTP-Binding Protein alpha Subunits, Gq-G11 - chemistry GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism Guanosine Triphosphate - metabolism Hardening Humans Hydrolysis Inactivation Lipid Metabolism Phospholipase Phospholipase C beta - chemistry Phospholipase C beta - metabolism Phosphorylation Protein Binding Protein Conformation Receptors, G-Protein-Coupled - metabolism Signal Transduction
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Description
Summary:	Harden et al examine C-beta signaling nodes with regard to the mechanism of activation and inactivation of Gq/phospholipase.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0009-2665 1520-6890
DOI:	10.1021/cr200209p