Statistical Treatment of Photon/Electron Counting: Extending the Linear Dynamic Range from the Dark Count Rate to Saturation

• Published in: Analytical chemistry (Washington) Vol. 82; no. 24; pp. 10129 - 10134
• Main Authors: Kissick, David J, Muir, Ryan D, Simpson, Garth J
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 15-12-2010
• Subjects: Analytical chemistry; Atoms & subatomic particles; Chemistry; Electrons; Exact sciences and technology; Experiments; General, instrumentation; Models, Statistical; Optics and Photonics - instrumentation; Optics and Photonics - methods; Photons; Poisson Distribution; Peak resolution; Photon counting; Poisson distribution; Conversion; Vertebrata; Signal; Detector; Treatment; Dynamics; Analog; Pisces; Distribution; Photomultiplier; Limit
• ISSN: 0003-2700; 1520-6882
• DOI: 10.1021/ac102219c

An experimentally simple photon counting method is demonstrated providing 7 orders of magnitude in linear dynamic range (LDR) for a single photomultiplier tube (PMT) detector. In conventional photon/electron counting methods, the linear range is dictated by the agreement between the binomially distributed measurement of counted events and the underlying Poisson distribution of photons/electrons. By explicitly considering the log-normal probability distribution in voltage transients as a function of the number of photons present and the Poisson distribution of photons, observed counts for a given threshold can be related to the mean number of photons well beyond the conventional limit. Analytical expressions are derived relating counts and photons that extend the linear range to an average of ∼11 photons arriving simultaneously with a single threshold. These expressions can be evaluated numerically for multiple thresholds extending the linear range to the saturation point of the PMT. The peak voltage distributions are experimentally shown to follow a Poisson weighted sum of log-normal distributions that can all be derived from the single photoelectron voltage peak-height distribution. The LDR that results from this method is compared to conventional single photon counting (SPC) and to signal averaging by analog to digital conversion (ADC).