Variation in Dialysis Facility Referral for Kidney Transplantation Among Patients With End-Stage Renal Disease in Georgia

• Published in: JAMA : the journal of the American Medical Association Vol. 314; no. 6; pp. 582 - 594
• Main Authors: Patzer, Rachel E, Plantinga, Laura C, Paul, Sudeshna, Gander, Jennifer, Krisher, Jenna, Sauls, Leighann, Gibney, Eric M, Mulloy, Laura, Pastan, Stephen O
• Format: Journal Article
• Language: English
• Published: United States American Medical Association 11-08-2015
• Subjects: Adolescent; Adult; Aged; Ambulatory Care Facilities - economics; Ambulatory Care Facilities - statistics & numerical data; Cohort Studies; Female; Georgia; Hemodialysis; Humans; Kidney diseases; Kidney Failure, Chronic - therapy; Kidney Transplantation; Male; Middle Aged; Poverty; Referral and Consultation - statistics & numerical data; Referrals; Renal Dialysis; Transplants & implants; Waiting Lists; Young Adult; Georgia; United States > US
• ISSN: 0098-7484; 1538-3598
• DOI: 10.1001/jama.2015.8897

IMPORTANCE: Dialysis facilities in the United States are required to educate patients with end-stage renal disease about all treatment options, including kidney transplantation. Patients receiving dialysis typically require a referral for kidney transplant evaluation at a transplant center from a dialysis facility to start the transplantation process, but the proportion of patients referred for transplantation is unknown. OBJECTIVE: To describe variation in dialysis facility–level referral for kidney transplant evaluation and factors associated with referral among patients initiating dialysis in Georgia, the US state with the lowest kidney transplantation rates. DESIGN, SETTING, AND PARTICIPANTS: Examination of United States Renal Data System data from a cohort of 15 279 incident, adult (18-69 years) patients with end-stage renal disease from 308 Georgia dialysis facilities from January 2005 to September 2011, followed up through September 2012, linked to kidney transplant referral data collected from adult transplant centers in Georgia in the same period. MAIN OUTCOMES AND MEASURES: Referral for kidney transplant evaluation within 1 year of starting dialysis at any of the 3 Georgia transplant centers was the primary outcome; placement on the deceased donor waiting list was also examined. RESULTS: The median within-facility percentage of patients referred within 1 year of starting dialysis was 24.4% (interquartile range, 16.7%-33.3%) and varied from 0% to 75.0%. Facilities in the lowest tertile of referral (<19.2%) were more likely to treat patients living in high-poverty neighborhoods (absolute difference, 21.8% [95% CI, 14.1%-29.4%]), had a higher patient to social worker ratio (difference, 22.5 [95% CI, 9.7-35.2]), and were more likely nonprofit (difference, 17.6% [95% CI, 7.7%-27.4%]) compared with facilities in the highest tertile of referral (>31.3%). In multivariable, multilevel analyses, factors associated with lower referral for transplantation, such as older age, white race, and nonprofit facility status, were not always consistent with the factors associated with lower waitlisting. CONCLUSIONS AND RELEVANCE: In Georgia overall, a limited proportion of patients treated with dialysis were referred for kidney transplant evaluation between 2005 and 2011, but there was substantial variability in referral among facilities. Variables associated with referral were not always associated with waitlisting, suggesting that different factors may account for disparities in referral.