Nickel-Catalyzed C‑Alkylation of Nitroalkanes with Unactivated Alkyl Iodides

Enabled by nickel catalysis, a mild and general catalytic method for C-alkylation of nitroalkanes with unactivated alkyl iodides is described. Compatible with primary, secondary, and tertiary alkyl iodides; and tolerant of a wide range of functional groups, this method allows rapid access to diverse...

Full description

Saved in:

Bibliographic Details
Published in:	Journal of the American Chemical Society Vol. 139; no. 24; pp. 8110 - 8113
Main Authors:	Rezazadeh, Sina, Devannah, Vijayarajan, Watson, Donald A
Format:	Journal Article
Language:	English
Published:	United States American Chemical Society 21-06-2017
Subjects:	Alkanes - chemistry Alkylation Catalysis Hydrocarbons, Iodinated - chemistry Molecular Structure Nickel - chemistry Nitro Compounds - chemistry
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Enabled by nickel catalysis, a mild and general catalytic method for C-alkylation of nitroalkanes with unactivated alkyl iodides is described. Compatible with primary, secondary, and tertiary alkyl iodides; and tolerant of a wide range of functional groups, this method allows rapid access to diverse nitroalkanes.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0002-7863 1520-5126
DOI:	10.1021/jacs.7b04312