Neuroleptic exposure following inpatient treatment of acute mania with lithium and neuroleptic

The authors examined continued neuroleptic exposure following inpatient treatment of mania with neuroleptics and lithium through structured chart review of 40 consecutive patients. At discharge, patients were receiving a mean of 793 mg/day (SD = 695) chlorpromazine equivalents; 6 months later they w...

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Bibliographic Details
Published in:	The American journal of psychiatry Vol. 151; no. 1; p. 133
Main Authors:	Sernyak, M J, Griffin, R A, Johnson, R M, Pearsall, H R, Wexler, B E, Woods, S W
Format:	Journal Article
Language:	English
Published:	United States 01-01-1994
Subjects:	Adult Aftercare Aged Ambulatory Care Antipsychotic Agents - administration & dosage Bipolar Disorder - drug therapy Drug Administration Schedule Drug Therapy, Combination Female Follow-Up Studies Hospitalization Humans Lithium - administration & dosage Male Middle Aged Retrospective Studies
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Summary:	The authors examined continued neuroleptic exposure following inpatient treatment of mania with neuroleptics and lithium through structured chart review of 40 consecutive patients. At discharge, patients were receiving a mean of 793 mg/day (SD = 695) chlorpromazine equivalents; 6 months later they were receiving a mean of 634 mg/day (SD = 684). This decrease was statistically significant, but the patients' ongoing neuroleptic exposure remained substantial.
ISSN:	0002-953X
DOI:	10.1176/ajp.151.1.133