Relative and Absolute Stereochemistry of the Didemnaketals, Metabolites of a Palauan Ascidian, Didemnum sp

The absolute stereochemistry of the heptaprenoids didemnaketals B (2) and C (3), isolated from a Palauan ascidian, was determined using a combination of degradation and derivatization experiments, chiral shift methods, and comparison of fragments to known compounds.

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Bibliographic Details
Published in:	Organic letters Vol. 4; no. 10; pp. 1699 - 1702
Main Authors:	Salomon, Christine E, Williams, David H, Lobkovsky, Emil, Clardy, Jon C, Faulkner, D. John
Format:	Journal Article
Language:	English
Published:	United States American Chemical Society 16-05-2002
Subjects:	Animals Anti-HIV Agents - chemistry Anti-HIV Agents - isolation & purification Anti-HIV Agents - pharmacology Crystallography, X-Ray Esters - chemistry Esters - isolation & purification Esters - pharmacology HIV-1 - drug effects Indicators and Reagents Magnetic Resonance Spectroscopy Models, Molecular Molecular Conformation Oxidation-Reduction Spiro Compounds - chemistry Spiro Compounds - isolation & purification Spiro Compounds - pharmacology Urochordata - chemistry
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Summary:	The absolute stereochemistry of the heptaprenoids didemnaketals B (2) and C (3), isolated from a Palauan ascidian, was determined using a combination of degradation and derivatization experiments, chiral shift methods, and comparison of fragments to known compounds.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1523-7060 1523-7052
DOI:	10.1021/ol025904z