Synthesis and Development of a Multifunctional Self-Decontaminating Polyurethane Coating

• Published in: ACS applied materials & interfaces Vol. 3; no. 6; pp. 2005 - 2011
• Main Authors: Wynne, James H, Fulmer, Preston A, McCluskey, D. Michelle, Mackey, Nicole M, Buchanan, J. Paige
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 22-06-2011
• Subjects: Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - pharmacology; Gram-Negative Bacteria - drug effects; Gram-Positive Bacteria - drug effects; Microbial Sensitivity Tests; Microscopy, Atomic Force; Polyurethanes - chemistry; Polyurethanes - pharmacology; Quaternary Ammonium Compounds - chemistry; Surface Properties; antimicrobial; self-decontaminating surfaces; coating; additives; biocide; dampening
• ISSN: 1944-8244; 1944-8252
• DOI: 10.1021/am200250d

A unique, durable, nonleaching antimicrobial urethane coating possessing energy-dampening properties is reported. Five novel diol-functionalized quaternary ammonium bromide salts were designed, synthesized, and cross-linked with a commercial polyisocyanate to afford novel multifunctional self-decontaminating coatings. Leaching of the antimicrobial into the environment is eliminated because of the biocidal tether. The effectiveness of these molecules to self-concentrate at the air–polymer interface without addition of other surface modifying additives proved extremely advantageous, and consequently resulted in microphase separation as confirmed by AFM. The coatings were designed to continuously decontaminate against a variety of pathogenic bacteria in addition to affording preliminary dampening properties. Minimum inhibitory concentration studies as well as surface antimicrobial evaluations were conducted using both Gram-positive and Gram-negative bacteria. Additionally, viscoelastic properties, hardness, tack, and surface energy measurements were used to correlate with coating performance.