Tough Antibacterial Metallopolymer Double-Network Hydrogels via Dual Polymerization

Tough Antibacterial Metallopolymer Double-Network Hydrogels via Dual Polymerization

We report the preparation of tough double-network (DN) metallopolymer antibacterial hydrogels through dual polymerization. DN hydrogels are composed of the first network of cationic cobaltocenium polyelectrolytes enabled using ring-opening metathesis polymerization and the second network of polymers...

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Bibliographic Details
Published in:Chemistry of materials Vol. 34; no. 12; pp. 5663 - 5672
Main Authors: Hwang, JiHyeon, Cha, Yujin, Ramos, Luis, Zhu, Tianyu, Buzoglu Kurnaz, Leman, Tang, Chuanbing
Format: Journal Article
Language:English
Published: American Chemical Society 28-06-2022
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Summary:We report the preparation of tough double-network (DN) metallopolymer antibacterial hydrogels through dual polymerization. DN hydrogels are composed of the first network of cationic cobaltocenium polyelectrolytes enabled using ring-opening metathesis polymerization and the second network of polymers prepared using radical polymerization. These DN hydrogels exhibited a very high compressive stress (up to ∼120 MPa). The introduction of boronic acid and ionic conjugation with β-lactam antibiotics endowed the hydrogels with high antimicrobial efficacy against both Gram-positive and Gram-negative bacteria.
ISSN:0897-4756
1520-5002
DOI:10.1021/acs.chemmater.2c00996