Molecules in Medicine: A Week-Long Multidisciplinary Summer Camp for High School Students

• Published in: Journal of chemical education Vol. 101; no. 4; pp. 1544 - 1550
• Main Authors: Timmons, Shannon C., Kuzmanov, Aleksandra
• Format: Journal Article
• Language: English
• Published: Easton American Chemical Society and Division of Chemical Education, Inc 09-04-2024; American Chemical Society
• Subjects: Adolescents; Aspirin; Biocompatibility; Biology; Camps; Careers; Chemistry; College students; Colleges & universities; Health Occupations; High School Students; Laboratory Experiments; Medicine; Natural products; Occupations; Organic Chemistry; Pharmaceutical sciences; Physicians; Science education; Scientific Research; Secondary School Science; Secondary school students; Students; Summer school; Teaching methods; Toxicity testing; Biotechnology; IR Spectroscopy; Interdisciplinary/Multidisciplinary; Biological Cells; Bioorganic Chemistry; Hands-On Learning/Manipulatives; Medicinal Chemistry; Instrumental Methods; Natural Products; Toxicology; Applications of Chemistry; Synthesis; Laboratory Instruction; High School/Introductory Chemistry; Curriculum; Drugs/Pharmaceuticals; Thin Layer Chromatography; Organic Chemistry
• ISSN: 0021-9584; 1938-1328
• DOI: 10.1021/acs.jchemed.3c01014

Health-related career goals are popular among high school science students, yet few understand the application of chemistry and biology research to the field of medicine and its impact on society. In this five-day multidisciplinary summer camp, high school students learn about the real-world relevance of medicinal chemistry research and its application to human health through a series of hands-on synthesis, isolation, and biological testing experiments. Our approach makes use of natural product related bioactive molecules, namely aspirin, oil of wintergreen, and eugenol, to highlight the connection between biology and chemistry in the field of medicinal chemistry. The subsequent analysis of these pharmaceutical agents via a variety of antibacterial testing, cell viability, and toxicity assays helps students understand the drug discovery process. In addition to laboratory experiments, students learn about various health professions through visits to Lawrence Technological University nursing and physician assistant program suites and a meeting with an experienced pre-health professions advisor. Through this unique ensemble of experiences, high school students gain valuable insights into the nature and impact of scientific research on the field of medicine and learn about a variety of health-related occupations. Participant survey responses indicate that students enjoyed learning about chemistry- and biology-related concepts and techniques related to the drug discovery process. Furthermore, this week-long summer camp met or exceeded all participants’ expectations, with many students expressing enhanced confidence in their scientific abilities.