Sesquiterpenes and Monoterpenes from the Bark of Inula m acrophylla

Eleven new sesquiterpenes (1−11) and two thymol derivatives (12, 13), along with 12 known sesquiterpenes and monoterpenes, were isolated from the bark of Inula macrophylla. Their structures were determined on the basis of spectral evidence (especially by HREIMS and 2D NMR) as well as chemical transf...

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Bibliographic Details
Published in:	Journal of natural products (Washington, D.C.) Vol. 64; no. 4; pp. 466 - 471
Main Authors:	Su, Bao-Ning, Takaishi, Yoshihisa, Yabuuchi, Tetsuya, Kusumi, Takenori, Tori, Motoo, Takaoka, Shigeru, Honda, Gisho, Ito, Michiho, Takeda, Yoshio, Kodzhimatov, Olimjon K, Ashurmetov, Ozodbek
Format:	Journal Article
Language:	English
Published:	American Chemical Society 27-04-2001
Online Access:	Get full text
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Summary:	Eleven new sesquiterpenes (1−11) and two thymol derivatives (12, 13), along with 12 known sesquiterpenes and monoterpenes, were isolated from the bark of Inula macrophylla. Their structures were determined on the basis of spectral evidence (especially by HREIMS and 2D NMR) as well as chemical transformations. The structure of macrophyllic acid A (1) was confirmed by X-ray analysis, and the absolute configuration of 1 was determined on the basis of the appropriate chemical conversions and the application of a modified Mosher's method.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np000211h