Persistent upregulation of brain phospho‐tau is accompanied by elevated hippocampal synaptic excitability and altered Ca2+ handling, following single or repeated closed‐head concussive impacts

Background Traumatic brain injury (TBI) is of widespread clinical concern and a significant risk factor for Alzheimer’s‐like dementia (AD). Notably, repeated concussions, vs. single concussions, have been shown to result in worsened and sustained neurological symptoms, including impaired cognition a...

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Bibliographic Details

Published in:	Alzheimer's & dementia Vol. 16
Main Author:	McDaid, John
Format:	Journal Article
Language:	English
Published:	01-12-2020
Online Access:	Get full text
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