上海380例家庭聚集性感染Omicron变异株的儿童及其家属临床特征分析
目的 分析亲子病房收治模式下,家庭聚集性感染Omicron变异株的儿童及其家属的临床特点及转归.方法 回顾性收集上海市第六人民医院新型冠状病毒肺炎(coronavirus disease 2019,COVID-19)定点医院于2022年4月8日至5月10日收治确诊的感染Omicron变异株患儿190例及其家属190例的临床资料,进行分析总结.结果 儿童组和成人组均以轻型为主,儿童组轻型比例高于成人组(P<0.05);2组临床表现均以上呼吸道症状为主,儿童组发热、腹痛腹泻、喘息发生率高于成人组(P<0.05),鼻塞流涕咳嗽、咽干咽痒咽痛发生率低于成人组(P<0.05);成人组治...
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Published in: | 中国当代儿科杂志 Vol. 24; no. 10; pp. 1085 - 1091 |
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Language: | Chinese |
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上海市第六人民医院儿科,上海 201306
2022
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Abstract | 目的 分析亲子病房收治模式下,家庭聚集性感染Omicron变异株的儿童及其家属的临床特点及转归.方法 回顾性收集上海市第六人民医院新型冠状病毒肺炎(coronavirus disease 2019,COVID-19)定点医院于2022年4月8日至5月10日收治确诊的感染Omicron变异株患儿190例及其家属190例的临床资料,进行分析总结.结果 儿童组和成人组均以轻型为主,儿童组轻型比例高于成人组(P<0.05);2组临床表现均以上呼吸道症状为主,儿童组发热、腹痛腹泻、喘息发生率高于成人组(P<0.05),鼻塞流涕咳嗽、咽干咽痒咽痛发生率低于成人组(P<0.05);成人组治疗连花清瘟颗粒/小儿豉翘清热颗粒、中药汤剂、重组人干扰素α2b喷雾剂、止咳化痰药、奈玛特韦/利托那韦片使用率均高于儿童组(P<0.05);儿童组疫苗接种率(30.5%)较成人组(71.1%)低(P<0.001),而儿童组严重急性呼吸综合征冠状病毒2(severe acute respiratory syndrome coronavirus 2,SARS-CoV-2)核酸阳性持续时间短于成人组(P<0.05).2组临床轻型者SARS-CoV-2核酸阳性持续时间短于普通型者(P<0.05).2组有基础疾病者SARS-CoV-2核酸阳性持续时间长于无基础疾病者(P<0.05).结论 家庭聚集性Omicron变异株感染儿童和成人的临床分型均以轻型为主.尽管儿童疫苗接种率较低,但在亲子病房收治模式中,疾病恢复较快,SARS-CoV-2核酸阳性持续时间短于成人. |
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AbstractList | 目的 分析亲子病房收治模式下,家庭聚集性感染Omicron变异株的儿童及其家属的临床特点及转归.方法 回顾性收集上海市第六人民医院新型冠状病毒肺炎(coronavirus disease 2019,COVID-19)定点医院于2022年4月8日至5月10日收治确诊的感染Omicron变异株患儿190例及其家属190例的临床资料,进行分析总结.结果 儿童组和成人组均以轻型为主,儿童组轻型比例高于成人组(P<0.05);2组临床表现均以上呼吸道症状为主,儿童组发热、腹痛腹泻、喘息发生率高于成人组(P<0.05),鼻塞流涕咳嗽、咽干咽痒咽痛发生率低于成人组(P<0.05);成人组治疗连花清瘟颗粒/小儿豉翘清热颗粒、中药汤剂、重组人干扰素α2b喷雾剂、止咳化痰药、奈玛特韦/利托那韦片使用率均高于儿童组(P<0.05);儿童组疫苗接种率(30.5%)较成人组(71.1%)低(P<0.001),而儿童组严重急性呼吸综合征冠状病毒2(severe acute respiratory syndrome coronavirus 2,SARS-CoV-2)核酸阳性持续时间短于成人组(P<0.05).2组临床轻型者SARS-CoV-2核酸阳性持续时间短于普通型者(P<0.05).2组有基础疾病者SARS-CoV-2核酸阳性持续时间长于无基础疾病者(P<0.05).结论 家庭聚集性Omicron变异株感染儿童和成人的临床分型均以轻型为主.尽管儿童疫苗接种率较低,但在亲子病房收治模式中,疾病恢复较快,SARS-CoV-2核酸阳性持续时间短于成人. |
Author | 国志 郑芳 李妙晨 卞相丽 吴志敏 陈娟娟 樊赛男 惠雷 张金萍 郭苗苗 蒋芹 张坤 |
AuthorAffiliation | 上海市第六人民医院儿科,上海 201306 |
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Author_FL | ZHENG Fang GUO Zhi WU Zhi-Min JIANG Qin BIAN Xiang-Li ZHANG Jin-Ping GUO Miao-Miao ZHANG Kun FAN Sai-Nan LI Miao-Chen HUI Lei CHEN Juan-Juan |
Author_FL_xml | – sequence: 1 fullname: BIAN Xiang-Li – sequence: 2 fullname: GUO Zhi – sequence: 3 fullname: ZHANG Kun – sequence: 4 fullname: LI Miao-Chen – sequence: 5 fullname: WU Zhi-Min – sequence: 6 fullname: JIANG Qin – sequence: 7 fullname: GUO Miao-Miao – sequence: 8 fullname: FAN Sai-Nan – sequence: 9 fullname: CHEN Juan-Juan – sequence: 10 fullname: HUI Lei – sequence: 11 fullname: ZHENG Fang – sequence: 12 fullname: ZHANG Jin-Ping |
Author_xml | – sequence: 1 fullname: 卞相丽 – sequence: 2 fullname: 国志 – sequence: 3 fullname: 张坤 – sequence: 4 fullname: 李妙晨 – sequence: 5 fullname: 吴志敏 – sequence: 6 fullname: 蒋芹 – sequence: 7 fullname: 郭苗苗 – sequence: 8 fullname: 樊赛男 – sequence: 9 fullname: 陈娟娟 – sequence: 10 fullname: 惠雷 – sequence: 11 fullname: 郑芳 – sequence: 12 fullname: 张金萍 |
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DocumentTitle_FL | Clinical features of children and their family members with family clusters of SARS-CoV-2 Omicron variant infection in Shanghai, China:an analysis of 380 cases |
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Keywords | 新型冠状病毒肺炎 Omicron变异株 家庭聚集性感染 临床特点 儿童 |
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