Low-cost electrochemical detection of -tyrosine using an rGO-Cu modified pencil graphite electrode and its surface orientation on a Ag electrode using an spectroelectrochemical method

• Published in: RSC advances Vol. 1; no. 39; pp. 22871 - 2288
• Main Authors: Kavitha, C, Bramhaiah, K, John, Neena S
• Format: Journal Article
• Language: English
• Published: 16-06-2020
• ISSN: 2046-2069
• DOI: 10.1039/d0ra04015k

A low cost reduced graphene oxide-copper hybrid nano thin-film modified Pencil Graphite Electrode has been employed to detect the
l
-tyrosine enantiomer. The free-standing rGO-Cu hybrid nano-thin film was prepared by a simple one-step liquid-liquid interface method. Electrochemical Cyclic Voltammetry, Differential Pulse Voltammetry, pH-dependent and scan rate dependent studies on bare PGE, Cu, rGO, and rGO-Cu for
l
-tyrosine have been explained in detail. The rGO-Cu modified PGE based biosensor exhibits good detection of
l
-tyrosine. The linear range detection limit was estimated to be 1 × 10
−7
M. The calculated sensitivity is 0.4 μA ppm
−1
mm
2
. This electroactive biosensor is easily fabricated and controlled and is cost-effective. The surface orientation of
l
-tyrosine on the Ag electrode at a particular potential and its comparison with vibrational DFT calculations have been studied for the first time.
A low cost reduced graphene oxide-copper hybrid nano thin-film modified pencil graphite electrode has been employed to detect the
l
-tyrosine enantiomer.