One-step methodology for the direct covalent capture of GPCRs from complex matrices onto solid surfaces based on the bioorthogonal reaction between haloalkane dehalogenase and chloroalkanesElectronic supplementary information (ESI) available. See DOI: 10.1039/c7sc03887a

Protein immobilization techniques play an important role in the development of assays for disease diagnosis and drug discovery. However, many of these approaches are not applicable to transmembrane proteins. G protein-coupled receptors (GPCRs) are the largest protein superfamily encoded by the human...

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Bibliographic Details

Main Authors:	Zeng, Kaizhu, Li, Qian, Wang, Jing, Yin, Guowei, Zhang, Yajun, Xiao, Chaoni, Fan, Taiping, Zhao, Xinfeng, Zheng, Xiaohui
Format:	Journal Article
Language:	English
Published:	03-01-2018
Online Access:	Get full text
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