IL-25 orchestrates activation of Thelper cells via conventional dendritic cells in tissue to exacerbate chronic HDM-induced asthma pathology

House dust mites (HDM) extract is a common trigger of asthma in humans. Chronic exposure to HDM also induces asthma-like pathology in mice. Allergic responses to HDM and other allergens are linked to release of IL-25, IL-33 and TSLP by epithelial cells; these cytokines, especially IL-33, target inna...

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Bibliographic Details

Published in:	The Journal of immunology (1950) Vol. 203; no. 8; pp. 2319 - 2327
Main Authors:	Claudio, Estefania, Wang, Hongshan, Kamenyeva, Olena, Tang, Wanhu, Ha, Hye-lin, Siebenlist, Ulrich
Format:	Journal Article
Language:	English
Published:	11-09-2019
Online Access:	Get full text
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