Triological Society Thesis Preclinical Validation of AR42, a Novel Histone Deacetylase Inhibitor, as Treatment for Vestibular Schwannomas

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Published in:The Laryngoscope Vol. 122; no. 1; pp. 174 - 189
Main Authors: Jacob, Abraham, Oblinger, Janet, Bush, Matthew L., Brendel, Victoria, Santarelli, Griffin, Chaudhury, Abhik R., Kulp, Samuel, La Perle, Krista M. D., Chen, Ching-Shih, Chang, Long-Sheng, Welling, D. Bradley
Format: Journal Article
Language:English
Published: 22-11-2011
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Author Brendel, Victoria
Bush, Matthew L.
Chaudhury, Abhik R.
Santarelli, Griffin
La Perle, Krista M. D.
Chang, Long-Sheng
Welling, D. Bradley
Jacob, Abraham
Oblinger, Janet
Chen, Ching-Shih
Kulp, Samuel
AuthorAffiliation 4 College of Medicine, The University of Toledo, Toledo, Ohio, USA
2 Center for Childhood Cancer, Nationwide Children’s Hospital, Columbus, Ohio, USA
7 Department of Veterinary Sciences, The Ohio State University, Columbus, Ohio, USA
3 Department of Otolaryngology – Head and Neck Surgery, University of Kentucky
8 Department of Surgery, Division of Otolaryngology, University of Arizona
5 Department of Pathology, The Ohio State University, Columbus, Ohio, USA
1 Department of Otolaryngology – Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA
6 College of Pharmacy, The Ohio State University, Columbus, Ohio, USA
AuthorAffiliation_xml – name: 7 Department of Veterinary Sciences, The Ohio State University, Columbus, Ohio, USA
– name: 2 Center for Childhood Cancer, Nationwide Children’s Hospital, Columbus, Ohio, USA
– name: 5 Department of Pathology, The Ohio State University, Columbus, Ohio, USA
– name: 6 College of Pharmacy, The Ohio State University, Columbus, Ohio, USA
– name: 3 Department of Otolaryngology – Head and Neck Surgery, University of Kentucky
– name: 8 Department of Surgery, Division of Otolaryngology, University of Arizona
– name: 1 Department of Otolaryngology – Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA
– name: 4 College of Medicine, The University of Toledo, Toledo, Ohio, USA
Author_xml – sequence: 1
  givenname: Abraham
  surname: Jacob
  fullname: Jacob, Abraham
  organization: Department of Otolaryngology – Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA Center for Childhood Cancer, Nationwide Children’s Hospital, Columbus, Ohio, USA Department of Otolaryngology – Head and Neck Surgery, University of Kentucky College of Medicine, The University of Toledo, Toledo, Ohio, USA Department of Pathology, The Ohio State University, Columbus, Ohio, USA College of Pharmacy, The Ohio State University, Columbus, Ohio, USA Department of Veterinary Sciences, The Ohio State University, Columbus, Ohio, USA Department of Surgery, Division of Otolaryngology, University of Arizona
– sequence: 2
  givenname: Janet
  surname: Oblinger
  fullname: Oblinger, Janet
  organization: Department of Otolaryngology – Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA Center for Childhood Cancer, Nationwide Children’s Hospital, Columbus, Ohio, USA Department of Otolaryngology – Head and Neck Surgery, University of Kentucky College of Medicine, The University of Toledo, Toledo, Ohio, USA Department of Pathology, The Ohio State University, Columbus, Ohio, USA College of Pharmacy, The Ohio State University, Columbus, Ohio, USA Department of Veterinary Sciences, The Ohio State University, Columbus, Ohio, USA Department of Surgery, Division of Otolaryngology, University of Arizona
– sequence: 3
  givenname: Matthew L.
  surname: Bush
  fullname: Bush, Matthew L.
  organization: Department of Otolaryngology – Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA Center for Childhood Cancer, Nationwide Children’s Hospital, Columbus, Ohio, USA Department of Otolaryngology – Head and Neck Surgery, University of Kentucky College of Medicine, The University of Toledo, Toledo, Ohio, USA Department of Pathology, The Ohio State University, Columbus, Ohio, USA College of Pharmacy, The Ohio State University, Columbus, Ohio, USA Department of Veterinary Sciences, The Ohio State University, Columbus, Ohio, USA Department of Surgery, Division of Otolaryngology, University of Arizona
– sequence: 4
  givenname: Victoria
  surname: Brendel
  fullname: Brendel, Victoria
  organization: Department of Otolaryngology – Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA Center for Childhood Cancer, Nationwide Children’s Hospital, Columbus, Ohio, USA Department of Otolaryngology – Head and Neck Surgery, University of Kentucky College of Medicine, The University of Toledo, Toledo, Ohio, USA Department of Pathology, The Ohio State University, Columbus, Ohio, USA College of Pharmacy, The Ohio State University, Columbus, Ohio, USA Department of Veterinary Sciences, The Ohio State University, Columbus, Ohio, USA Department of Surgery, Division of Otolaryngology, University of Arizona
– sequence: 5
  givenname: Griffin
  surname: Santarelli
  fullname: Santarelli, Griffin
  organization: Department of Otolaryngology – Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA Center for Childhood Cancer, Nationwide Children’s Hospital, Columbus, Ohio, USA Department of Otolaryngology – Head and Neck Surgery, University of Kentucky College of Medicine, The University of Toledo, Toledo, Ohio, USA Department of Pathology, The Ohio State University, Columbus, Ohio, USA College of Pharmacy, The Ohio State University, Columbus, Ohio, USA Department of Veterinary Sciences, The Ohio State University, Columbus, Ohio, USA Department of Surgery, Division of Otolaryngology, University of Arizona
– sequence: 6
  givenname: Abhik R.
  surname: Chaudhury
  fullname: Chaudhury, Abhik R.
  organization: Department of Otolaryngology – Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA Center for Childhood Cancer, Nationwide Children’s Hospital, Columbus, Ohio, USA Department of Otolaryngology – Head and Neck Surgery, University of Kentucky College of Medicine, The University of Toledo, Toledo, Ohio, USA Department of Pathology, The Ohio State University, Columbus, Ohio, USA College of Pharmacy, The Ohio State University, Columbus, Ohio, USA Department of Veterinary Sciences, The Ohio State University, Columbus, Ohio, USA Department of Surgery, Division of Otolaryngology, University of Arizona
– sequence: 7
  givenname: Samuel
  surname: Kulp
  fullname: Kulp, Samuel
  organization: Department of Otolaryngology – Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA Center for Childhood Cancer, Nationwide Children’s Hospital, Columbus, Ohio, USA Department of Otolaryngology – Head and Neck Surgery, University of Kentucky College of Medicine, The University of Toledo, Toledo, Ohio, USA Department of Pathology, The Ohio State University, Columbus, Ohio, USA College of Pharmacy, The Ohio State University, Columbus, Ohio, USA Department of Veterinary Sciences, The Ohio State University, Columbus, Ohio, USA Department of Surgery, Division of Otolaryngology, University of Arizona
– sequence: 8
  givenname: Krista M. D.
  surname: La Perle
  fullname: La Perle, Krista M. D.
  organization: Department of Otolaryngology – Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA Center for Childhood Cancer, Nationwide Children’s Hospital, Columbus, Ohio, USA Department of Otolaryngology – Head and Neck Surgery, University of Kentucky College of Medicine, The University of Toledo, Toledo, Ohio, USA Department of Pathology, The Ohio State University, Columbus, Ohio, USA College of Pharmacy, The Ohio State University, Columbus, Ohio, USA Department of Veterinary Sciences, The Ohio State University, Columbus, Ohio, USA Department of Surgery, Division of Otolaryngology, University of Arizona
– sequence: 9
  givenname: Ching-Shih
  surname: Chen
  fullname: Chen, Ching-Shih
  organization: Department of Otolaryngology – Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA Center for Childhood Cancer, Nationwide Children’s Hospital, Columbus, Ohio, USA Department of Otolaryngology – Head and Neck Surgery, University of Kentucky College of Medicine, The University of Toledo, Toledo, Ohio, USA Department of Pathology, The Ohio State University, Columbus, Ohio, USA College of Pharmacy, The Ohio State University, Columbus, Ohio, USA Department of Veterinary Sciences, The Ohio State University, Columbus, Ohio, USA Department of Surgery, Division of Otolaryngology, University of Arizona
– sequence: 10
  givenname: Long-Sheng
  surname: Chang
  fullname: Chang, Long-Sheng
  organization: Department of Otolaryngology – Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA Center for Childhood Cancer, Nationwide Children’s Hospital, Columbus, Ohio, USA Department of Otolaryngology – Head and Neck Surgery, University of Kentucky College of Medicine, The University of Toledo, Toledo, Ohio, USA Department of Pathology, The Ohio State University, Columbus, Ohio, USA College of Pharmacy, The Ohio State University, Columbus, Ohio, USA Department of Veterinary Sciences, The Ohio State University, Columbus, Ohio, USA Department of Surgery, Division of Otolaryngology, University of Arizona
– sequence: 11
  givenname: D. Bradley
  surname: Welling
  fullname: Welling, D. Bradley
  organization: Department of Otolaryngology – Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA Center for Childhood Cancer, Nationwide Children’s Hospital, Columbus, Ohio, USA Department of Otolaryngology – Head and Neck Surgery, University of Kentucky College of Medicine, The University of Toledo, Toledo, Ohio, USA Department of Pathology, The Ohio State University, Columbus, Ohio, USA College of Pharmacy, The Ohio State University, Columbus, Ohio, USA Department of Veterinary Sciences, The Ohio State University, Columbus, Ohio, USA Department of Surgery, Division of Otolaryngology, University of Arizona
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Title Triological Society Thesis Preclinical Validation of AR42, a Novel Histone Deacetylase Inhibitor, as Treatment for Vestibular Schwannomas
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