Cell-autonomous requirement for DNaseII in non-apoptotic cell death

DNA fragmentation is a critical component of apoptosis but it has not been characterized in non-apoptotic forms of cell death, such as necrosis and autophagic cell death. In mammalian apoptosis, caspase activated DNase (CAD) cleaves DNA into nucleosomal fragments in dying cells, and subsequently DNa...

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Bibliographic Details
Published in:Cell death and differentiation Vol. 16; no. 10; pp. 1362 - 1371
Main Authors: Bass, B. Paige, Tanner, Elizabeth A., Martín, Daniel Mateos San, Blute, Todd, Kinser, Ronald D., Dolph, Patrick J., McCall, Kimberly
Format: Journal Article
Language:English
Published: 26-06-2009
Online Access:Get full text
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