Inhibition of Superoxide Generation upon TCR Engagement Rescues Mart-127-35 reactive T cells from Activation Induced Cell Death

Cytolytic T lymphocytes (CTL) undergo massive expansion upon appropriate antigenic stimulation. Homeostasis is maintained by a subsequent “contraction” of these cells. Activation-induced cell death (AICD) and programmed cell death, prevent the untoward side effects arising from excessive numbers and...

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Bibliographic Details
Published in:Cancer research (Chicago, Ill.) Vol. 69; no. 15; pp. 6282 - 6289
Main Authors: Norell, Håkan, da Palma, Telma Martins, Lesher, Aaron, Kaur, Navtej, Mehrotra, Meenal, Naga, Osama S., Spivey, Natalie, Olafimihan, Seye, Chakraborty, Nitya G., Voelkel-Johnson, Christina, Nishimura, Michael I., Mukherji, Bijay, Mehrotra, Shikhar
Format: Journal Article
Language:English
Published: 28-07-2009
Online Access:Get full text
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