A chemical typhoid vaccine containing a surface-antigen complex including the K-antigen

A new chemical typhoid vaccine containing the complex of surface Vi- and K-antigens has been obtained and experimentally studied. The vaccine has been found to possess high immunogenic and antigenic potency. Typhoid complex vaccine containing K-antigen stimulates the development of anti-infection an...

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Bibliographic Details
Published in:	Žurnal mikrobiologii, ėpidemiologii i immunobiologii no. 1; p. 51
Main Authors:	Stepanova, L K, Belaia, Iu A, Sergeeva, N S, Ageeva, V A, Petrukhin, V G
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-01-1993
Subjects:	Animals Antigens, Bacterial - immunology Antigens, Surface - immunology Dose-Response Relationship, Immunologic Drug Evaluation, Preclinical Immunization Mice O Antigens Polysaccharides, Bacterial - immunology Rabbits Salmonella typhi - immunology Time Factors Typhoid Fever - prevention & control Typhoid-Paratyphoid Vaccines - administration & dosage Typhoid-Paratyphoid Vaccines - immunology Typhoid-Paratyphoid Vaccines - toxicity Vaccines, Synthetic - administration & dosage Vaccines, Synthetic - immunology Vaccines, Synthetic - toxicity
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Summary:	A new chemical typhoid vaccine containing the complex of surface Vi- and K-antigens has been obtained and experimentally studied. The vaccine has been found to possess high immunogenic and antigenic potency. Typhoid complex vaccine containing K-antigen stimulates the development of anti-infection and postvaccinal complex.
ISSN:	0372-9311