Ligand-dependent intracellular trafficking of the G protein-coupled P2Y 6 receptor

Endosomal trafficking is intricately linked to G protein-coupled receptors (GPCR) fate and signaling. Extracellular uridine diphosphate (UDP) acts as a signaling molecule by selectively activating the GPCR P2Y . Despite the recent interest for this receptor in pathologies, such as gastrointestinal a...

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Bibliographic Details

Published in:	Biochimica et biophysica acta. Molecular cell research Vol. 1870; no. 5; p. 119476
Main Authors:	Girard, Mélissa, Bellefeuille, Steve Dagenais, Eiselt, Émilie, Arguin, Guillaume, Longpré, Jean-Michel, Sarret, Philippe, Gendron, Fernand-Pierre
Format:	Journal Article
Language:	English
Published:	Netherlands 01-06-2023
Subjects:	GTP-Binding Proteins - metabolism Humans Ligands Receptors, G-Protein-Coupled - genetics Receptors, G-Protein-Coupled - metabolism Uridine Diphosphate - metabolism G protein-coupled receptors Internalization P2Y receptor Trafficking Ligands Endosomes
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