Maternal 5 m CpG Imprints at the PARD6G-AS1 and GCSAML Differentially Methylated Regions Are Decoupled From Parent-of-Origin Expression Effects in Multiple Human Tissues

A hallmark of imprinted genes in mammals is the occurrence of parent-of-origin-dependent asymmetry of DNA cytosine methylation (5 C) of alleles at CpG islands (CGIs) in their promoter regions. This 5 CpG asymmetry between the parental alleles creates allele-specific imprinted differentially methylat...

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Bibliographic Details

Published in:	Frontiers in genetics Vol. 9; p. 36
Main Authors:	de Sá Machado Araújo, Graziela, da Silva Francisco Junior, Ronaldo, Dos Santos Ferreira, Cristina, Mozer Rodrigues, Pedro Thyago, Terra Machado, Douglas, Louvain de Souza, Thais, Teixeira de Souza, Jozimara, Figueiredo Osorio da Silva, Cleiton, Alves da Silva, Antônio Francisco, Andrade, Claudia Caixeta Franco, da Silva, Alan Tardin, Ramos, Victor, Garcia, Ana Beatriz, Machado, Filipe Brum, Medina-Acosta, Enrique
Format:	Journal Article
Language:	English
Published:	Switzerland 2018
Subjects:	OR2L13 GCSAML GRB10 imprinting disease PARD6G-AS1 genomic imprinting ZNF124 LOC284240
Online Access:	Get full text
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