$Utility of 18 F-fluoroestradiol ( 18 F-FES) PET/CT imaging as a pharmacodynamic marker in patients with refractory estrogen receptor-positive solid tumors receiving Z-endoxifen therapy$
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Utility of 18 F-fluoroestradiol ( 18 F-FES) PET/CT imaging as a pharmacodynamic marker in patients with refractory estrogen receptor-positive solid tumors receiving Z-endoxifen therapy

Z-endoxifen is the most potent of the metabolites of tamoxifen, and has the potential to be more effective than tamoxifen because it bypasses potential drug resistance mechanisms attributable to patient variability in the expression of the hepatic microsomal enzyme CYP2D6. F-FES is a positron emissi...

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Bibliographic Details
Published in:	European journal of nuclear medicine and molecular imaging Vol. 44; no. 3; p. 500
Main Authors:	Lin, Frank I, Gonzalez, E M, Kummar, S, Do, K, Shih, J, Adler, S, Kurdziel, K A, Ton, A, Turkbey, B, Jacobs, P M, Bhattacharyya, S, Chen, A P, Collins, J M, Doroshow, J H, Choyke, P L, Lindenberg, M L
Format:	Journal Article
Language:	English
Published:	Germany 01-03-2017
Subjects:	Adult Aged Breast Neoplasms - diagnostic imaging Breast Neoplasms - drug therapy Breast Neoplasms - genetics Breast Neoplasms, Male - diagnostic imaging Breast Neoplasms, Male - drug therapy Breast Neoplasms, Male - genetics Estradiol - analogs & derivatives Estrogen Antagonists - therapeutic use Female Genital Neoplasms, Female - diagnostic imaging Genital Neoplasms, Female - drug therapy Genital Neoplasms, Female - genetics Humans Male Middle Aged Positron Emission Tomography Computed Tomography Radiopharmaceuticals Receptors, Estrogen - antagonists & inhibitors Receptors, Estrogen - genetics Tamoxifen - analogs & derivatives Tamoxifen - therapeutic use Z-endoxifen Positron emission tomography (PET) 18F-FES Pharmacodynamic marker Fluoroestradiol
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