Synthesis and immunotropic activity of methyl esters of 2-alkylaminomethylene-3-oxolup-20(29)-en-28-ic acids

New lupane beta-enaminoketones were synthesized by interaction of methyl 2-hydroxymethylene-3-oxolup-20(29)-en-28-oate with aliphatic amines. Immunotropic activity was found for some of these compounds.

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Bibliographic Details
Published in:	Bioorganicheskaia khimiia Vol. 34; no. 4; p. 540
Main Authors:	Tolmacheva, I A, Anikina, L V, Vikharev, Iu B, Igosheva, E V, Shelepen'kina, L N, Grishko, V V, Tolstikov, A G
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-07-2008
Subjects:	Animals Antibody Formation Esters Immunity, Cellular Immunosuppressive Agents - chemical synthesis Immunosuppressive Agents - chemistry Immunosuppressive Agents - immunology Ketones - chemical synthesis Ketones - immunology Magnetic Resonance Spectroscopy Male Mice Spectrophotometry, Infrared Structure-Activity Relationship Triterpenes - chemical synthesis Triterpenes - chemistry Triterpenes - immunology
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Summary:	New lupane beta-enaminoketones were synthesized by interaction of methyl 2-hydroxymethylene-3-oxolup-20(29)-en-28-oate with aliphatic amines. Immunotropic activity was found for some of these compounds.
ISSN:	0132-3423