Hepatitis C virus infection among pregnant women in Central-Western Brazil, 2005-2007

• Published in: Revista de saúde pública Vol. 45; no. 5; pp. 974 - 976
• Main Authors: Pinto, C S, Martins, RMB, de Andrade, SMO, Stief, ACF, de Oliveira, RD, de Castro, ARCM
• Format: Journal Article
• Language: Portuguese
• Published: 01-10-2011
• Subjects: Hepatitis C virus
• ISSN: 0034-8910

The study was aimed at estimating the prevalence of infection with and the genotype of hepatitis C virus (HCV), and to determine the extent of underreporting of HCV cases. A total of 115,386 pregnant women seen by the Program for Protection of Pregnancy [Programa Estadual de Protecao a Gestante] of the state of Mato Grosso do Sul, Central-Western Brazil, were tested for anti-HCV antibodies between 2005 and 2007. Prevalence of HCV infection was 1.07 cases per thousand. Positive samples were tested for HCV RNA and genotyped. Genotype 1 was detected in 73% of samples, genotype 3 in 24.3%, and genotype 2 in 2.7%. Underreporting of hepatitis C cases was 35.5%.Original Abstract: O estudo teve por objetivo estimar a prevalencia da infeccao e genotipo do virus da hepatite C (HCV), bem como determinar a subnotificacao de casos. O total de 115.386 gestantes atendidas pelo Programa Estadual de Protecao a Gestante de Mato Grosso do Sul foi submetido a coleta de sangue para a deteccao de anti-HCV, de 2005 a 2007. A prevalencia da infeccao pelo HCV foi de 1,07 casos/1.000. As amostras positivas foram submetidas a deteccao do HCV-RNA e genotipadas. O genotipo 1 foi encontrado em 73% das amostras, 24,3% pertenciam ao genotipo 3 e 2,7% ao genotipo 2. A subnotificacao de casos de hepatite C foi de 35,5%..