Selective tumor blood-brain barrier opening with the kinin B2 receptor agonist [Phe super(8)[psi](CH sub(2)NH)Arg super(9)]-BK in a F98 glioma rat model: An MRI study

Treatment of malignant glioma with chemotherapy is limited mostly because of delivery impediment related to the blood-brain barrier (BBB). One approach for transporting drugs across the BBB involves the activation of bradykinin-B2 receptors (BK-B2R). Our objective was to pharmacologically characteri...

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Bibliographic Details

Published in:	Neuropeptides (Edinburgh) Vol. 44; no. 2; pp. 177 - 185
Main Authors:	Cote, Jerome, Savard, Martin, Bovenzi, Veronica, Dubuc, Celena, Tremblay, Luc, Tsanaclis, Ana Maria, tin, David, Lepage, Martin, Gobeil, Fernand
Format:	Journal Article
Language:	English
Published:	01-04-2010
Online Access:	Get full text
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