Refractory Colitis Following Anti-CTLA4 Antibody Therapy: Analysis of Mucosal FOXP3 super(+) T Cells

Ipilimumab is a humanized antibody to CTLA4 and is used to treat cancers refractory to conventional treatment. We treated 21 patients with refractory melanoma or prostate cancer with anti-CTLA4 antibody (ipilimumab), with subsequent development of significant colitis in nine cases. Two of these nine...

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Bibliographic Details

Published in:	Digestive diseases and sciences Vol. 55; no. 5; pp. 1396 - 1405
Main Authors:	Lord, James D, Hackman, Robert C, Moklebust, Amanda, Thompson, John A, Higano, Celestia S, Chielens, Deborah, Steinbach, Gideon, McDonald, George B
Format:	Journal Article
Language:	English
Published:	01-05-2010
Online Access:	Get full text
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