Search for altered sodium channel gating kinetics in magnetically stimulated voltage-clamped N1E-115 cells

The whole-cell patch-clamp technique was used to study sodium channel gating kinetics in NIE-115 neuroblastoma cells during application of 2 Tesla 84 mu s zero-to-peak magnetic fields. A technique using net charge measurements was developed to detect small transient changes in membrane current durin...

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Published in:IEEE, PISCATAWAY, NJ, (USA). no. 437-1438. 1993 no. 437-1438
Main Authors: Wolf, Erich WII, Walker, Cedric F, Ide, Charles F
Format: Conference Proceeding
Language:English
Published: 01-01-1993
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Abstract The whole-cell patch-clamp technique was used to study sodium channel gating kinetics in NIE-115 neuroblastoma cells during application of 2 Tesla 84 mu s zero-to-peak magnetic fields. A technique using net charge measurements was developed to detect small transient changes in membrane current during application of magnetic stimuli. No evidence was found to suggest that the magnetic filed can influence channel gating.
AbstractList The whole-cell patch-clamp technique was used to study sodium channel gating kinetics in NIE-115 neuroblastoma cells during application of 2 Tesla 84 mu s zero-to-peak magnetic fields. A technique using net charge measurements was developed to detect small transient changes in membrane current during application of magnetic stimuli. No evidence was found to suggest that the magnetic filed can influence channel gating.
Author Wolf, Erich WII
Ide, Charles F
Walker, Cedric F
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  givenname: Charles
  surname: Ide
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  fullname: Ide, Charles F
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Snippet The whole-cell patch-clamp technique was used to study sodium channel gating kinetics in NIE-115 neuroblastoma cells during application of 2 Tesla 84 mu s...
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Title Search for altered sodium channel gating kinetics in magnetically stimulated voltage-clamped N1E-115 cells
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