Search for altered sodium channel gating kinetics in magnetically stimulated voltage-clamped N1E-115 cells

Search for altered sodium channel gating kinetics in magnetically stimulated voltage-clamped N1E-115 cells

The whole-cell patch-clamp technique was used to study sodium channel gating kinetics in NIE-115 neuroblastoma cells during application of 2 Tesla 84 mu s zero-to-peak magnetic fields. A technique using net charge measurements was developed to detect small transient changes in membrane current durin...

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Bibliographic Details
Published in:IEEE, PISCATAWAY, NJ, (USA). no. 437-1438. 1993 no. 437-1438
Main Authors: Wolf, Erich WII, Walker, Cedric F, Ide, Charles F
Format: Conference Proceeding
Language:English
Published: 01-01-1993
Online Access:Get full text
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Summary:The whole-cell patch-clamp technique was used to study sodium channel gating kinetics in NIE-115 neuroblastoma cells during application of 2 Tesla 84 mu s zero-to-peak magnetic fields. A technique using net charge measurements was developed to detect small transient changes in membrane current during application of magnetic stimuli. No evidence was found to suggest that the magnetic filed can influence channel gating.
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ISBN:0780313771
9780780313774