Systemic Lupus Erythematosus and Lupus Nephritis Presenting as Severe Constitutional Symptoms

Systemic lupus erythematosus (SLE) is a remitting-relapsing systemic autoantibody and immune complex disease with a similar clinical presentation to that of malignancy and infection. The authors report a case of newly diagnosed SLE and lupus nephritis in a 48-year-old woman with constitutional sympt...

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Bibliographic Details
Published in:Cureus Vol. 16; no. 3; p. e56670
Main Authors: La, Ton, Ansari, Sahifah, Ha, Ethan, Novakovic, Matthew
Format: Report
Language:English
Published: 01-03-2024
Online Access:Get full text
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Summary:Systemic lupus erythematosus (SLE) is a remitting-relapsing systemic autoantibody and immune complex disease with a similar clinical presentation to that of malignancy and infection. The authors report a case of newly diagnosed SLE and lupus nephritis in a 48-year-old woman with constitutional symptoms and unintentional weight loss. Her presentation was further complicated by pericardial effusion and methicillin-resistant Staphylococcus aureus (MRSA) facial cellulitis and bacteremia. In the context of nonspecific symptoms and a wide initial differential diagnosis, the early consideration of rheumatologic etiologies and the involvement of consultant services led to appropriate diagnostic testing and a timely diagnosis.
Bibliography:ObjectType-Case Study-2
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ObjectType-Report-1
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.56670