A Rare Intersection: A Case of Gastric Adenocarcinoma With Yolk Sac Differentiation

• Published in: Cureus Vol. 15; no. 9; p. e46019
• Main Authors: Taslim, Sanzida, Rimin, Nishat, James, Aimen, Anika, Nabila N, Naz, Javeria, Shehryar, Abdullah, Rehman, Abdur
• Format: Report
• Language: English
• Published: 01-09-2023
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.46019

This case report presents a rare instance of a 73-year-old male diagnosed with a yolk sac tumor (YST) coexisting with adenocarcinoma components in the stomach. YSTs are primarily gonadal and seldom occur in extragonadal sites such as the gastrointestinal tract. The patient underwent curative resection followed by chemotherapy, resulting in long-term survival without recurrence. This case contributes to the limited existing literature on gastric YSTs, emphasizing the importance of early diagnosis and effective treatment for this aggressive malignancy. It serves as a valuable addition to our understanding of the pathophysiology, diagnosis, and management of this rare condition.