Could 68 Ga-DOTA-UBI-29-41 Help Identify Chronic Osteomyelitis on PET/CT Images? A Pilot Study

ABSTRACTThis pilot study aimed to confirm the presence of infectious agents in infection foci using PET/CT imaging with 68 Ga-DOTA-UBI (29-41) in 7 patients with chronic osteomyelitis and with indications for surgical cleaning at the site of the infection focus. The whole-body PET/CT was performed o...

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Bibliographic Details
Published in:	Clinical nuclear medicine Vol. 48; no. 11; pp. 982 - 984
Main Authors:	Nogueira, Solange Amorim, de Barboza, Marycel F, Dell'Aquila, Adriana M, Santos, Durval C B, Osawa, Akemi
Format:	Journal Article
Language:	English
Published:	01-11-2023
Online Access:	Get full text
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Summary:	ABSTRACTThis pilot study aimed to confirm the presence of infectious agents in infection foci using PET/CT imaging with 68 Ga-DOTA-UBI (29-41) in 7 patients with chronic osteomyelitis and with indications for surgical cleaning at the site of the infection focus. The whole-body PET/CT was performed on Biograph mCT 40 PET/CT scanner (Siemens Healthineers); the image began 45-60 minutes postinjection of the radiotracer (148-260 MBq). This study demonstrated that, in 6 patients in whom the PET/CT was classified as positive for identified infectious foci, confirmed by culture of the secretion sample collected during surgery, only 1 patient in antibiotic therapy was negative.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 content type line 23 ObjectType-Feature-2
ISSN:	1536-0229
DOI:	10.1097/RLU.0000000000004866