No evidence of long-term immunosuppression after high-titer Edmonston-Zagreb measles vaccination in Senegal

In measles vaccine trials in Guinea-Bissau, Senegal, and Haiti, girls who received high-titer Edmonston-Zagreb (EZ; > 10 super(4.7) infectious particles) or Schwarz measles vaccines at 4-6 months of age had a higher mortality than girls receiving standard measles vaccine at 9-10 months of age. We...

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Bibliographic Details
Published in:	The Journal of infectious diseases Vol. 171; no. 2; pp. 506 - 508
Main Authors:	Samb, B, Whittle, H, Aaby, P, Coll Seck, AM, Bennett, J, Markowitz, L, Ngom, Pa Tamba, Zeller, H, Michaelsen, K F, Simondon, F
Format:	Journal Article
Language:	English
Published:	01-01-1995
Subjects:	Senegal
Online Access:	Get full text
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Summary:	In measles vaccine trials in Guinea-Bissau, Senegal, and Haiti, girls who received high-titer Edmonston-Zagreb (EZ; > 10 super(4.7) infectious particles) or Schwarz measles vaccines at 4-6 months of age had a higher mortality than girls receiving standard measles vaccine at 9-10 months of age. We used several different tests with the objectives of finding immunologic differences between the vaccine groups and identifying possible defects that could be corrected through specific interventions (e.g., vitamin A supplementation or nutritional rehabilitation).
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 content type line 23 ObjectType-Feature-1
ISSN:	0022-1899