Stage-Dependent Expression and Up-Regulation of Trypanothione Synthetase in Amphotericin B Resistant Leishmania donovani: e97600

Kinetoplastids differ from other organisms in their ability to conjugate glutathione and spermidine to form trypanothione which is involved in maintaining redox homeostasis and removal of toxic metabolites. It is also involved in drug resistance, antioxidant mechanism, and defense against cellular o...

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Bibliographic Details

Published in:	PloS one Vol. 9; no. 6
Main Authors:	Equbal, Asif, Suman, Shashi Shekhar, Anwar, Shadab, Singh, Krishn Pratap, Zaidi, Amir, Sardar, Abul Hasan, Das, Pradeep, Ali, Vahab
Format:	Journal Article
Language:	English
Published:	01-06-2014
Subjects:	Leishmania donovani
Online Access:	Get full text
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