Mycobactericidal Activity of Sutezolid (PNU-100480) in Sputum (EBA) and Blood (WBA) of Patients with Pulmonary Tuberculosis: e94462

Rationale Sutezolid (PNU-100480) is a linezolid analog with superior bactericidal activity against Mycobacterium tuberculosis in the hollow fiber, whole blood and mouse models. Like linezolid, it is unaffected by mutations conferring resistance to standard TB drugs. This study of sutezolid is its fi...

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Bibliographic Details
Published in:PloS one Vol. 9; no. 4
Main Authors: Wallis, Robert S, Dawson, Rodney, Friedrich, Sven O, Venter, Amour, Paige, Darcy, Zhu, Tong, Silvia, Annette, Gobey, Jason, Ellery, Craig, Zhang, Yao
Format: Journal Article
Language:English
Published: 01-04-2014
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