Novel fluorine-18 PET radiotracers based on flumazenil for GABA sub(A) imaging in the brain

Introduction: Two 7-fluoroimidazobenzodiazepines (AH114726 and GEH120348), analogs of flumazenil, were labeled with fluorine-18 and evaluated as alternative radioligands for in vivo imaging of the GABA sub(A)/benzodiazepine receptor by comparing them to [ super(11)C]flumazenil in rhesus monkey. Meth...

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Bibliographic Details
Published in:Nuclear medicine and biology Vol. 40; no. 7; pp. 901 - 905
Main Authors: Rodnick, ME, Hockley, B G, Sherman, P, Quesada, C, Battle, M R, Jackson, A, Linder, KE, Macholl, S, Trigg, W J, Kilbourn, M R, Scott, PJH
Format: Journal Article
Language:English
Published: 01-10-2013
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