Identification of vascular postsynaptic alpha sub(1)- and alpha sub(2)-adrenoceptors in man

Identification of vascular postsynaptic alpha sub(1)- and alpha sub(2)-adrenoceptors in man

The authors studied postsynaptic alpha -adrenoceptors in human blood vessels by measuring the influence on forearm blood flow induced by intra-arterial infusions of selective alpha sub(1)- and alpha sub(2)-adrenoceptor agonists (methoxamine, B-HT 933, clonidine and guanfacine) and antagonists (doxaz...

Full description

Saved in:
Bibliographic Details
Published in:Circulation research Vol. 54; no. 4; pp. 447 - 452
Main Authors: Jie, K, van Brummelen, P, Vermey, P, Timmermans, P B, van Zwieten, PA
Format: Journal Article
Language:English
Published: 01-01-1984
Subjects:
alpha -adrenergic
blood vessels
man
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The authors studied postsynaptic alpha -adrenoceptors in human blood vessels by measuring the influence on forearm blood flow induced by intra-arterial infusions of selective alpha sub(1)- and alpha sub(2)-adrenoceptor agonists (methoxamine, B-HT 933, clonidine and guanfacine) and antagonists (doxazosin and yohimbine). The findings provide strong evidence for the existence of postsynaptic alpha sub(1)- as well as alpha sub(2)-adrenoceptor, both mediating vasoconstriction and contributing to basal vascular tone.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
content type line 23
ObjectType-Feature-1
ISSN:0009-7330