New arachidonate-derived lipid mediators: The "isoprostanes". Synthesis and measurement

Recently, a new class of compounds, the isoprostanes (IP), have been described. These isoprostanes, isomeric with biologically active prostaglandins (PGs), are produced in vivo by a cyclooxygenase (COX) independent free-radical mechanism. The isoprostanes, formed in situ on phospholipids by peroxida...

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Bibliographic Details
Main Author: Adiyaman, Mustafa
Format: Dissertation
Language:English
Published: ProQuest Dissertations & Theses 01-01-1997
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