New arachidonate-derived lipid mediators: The "isoprostanes". Synthesis and measurement
Recently, a new class of compounds, the isoprostanes (IP), have been described. These isoprostanes, isomeric with biologically active prostaglandins (PGs), are produced in vivo by a cyclooxygenase (COX) independent free-radical mechanism. The isoprostanes, formed in situ on phospholipids by peroxida...
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Format: | Dissertation |
Language: | English |
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ProQuest Dissertations & Theses
01-01-1997
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Online Access: | Get full text |
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