Antagonism and synergism detection in multidimensional quantal response surfaces

In this dissertation methods described in the literature to model and test for antagonism, synergism and independence (ASI) are reviewed. Stochastic approximation techniques applied to a radial design are investigated for determining ASI by estimating a contour of constant probability. Monte Carlo e...

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Bibliographic Details

Main Author:	Parks, Thomas P
Format:	Dissertation
Language:	English
Published:	ProQuest Dissertations & Theses 01-01-1998
Subjects:	Biostatistics Statistics Toxicology
Online Access:	Get full text
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