The characterization of the structure of the active reactive site loop of alpha1-antitrypsin by multidimensional NMR methods

Serpins are a family of related proteins most of which act as specific inhibitors of serine proteinases. The details of the inhibitory mechanism of serpins are not well understood, in part, due to little direct structural information about the active form of any serpin. The application of multidimen...

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Bibliographic Details
Main Author: Patera, Alexandra Sacha
Format: Dissertation
Language:English
Published: ProQuest Dissertations & Theses 01-01-1994
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